ncRNA name | KChIP3 siRNA |
ncRNA Category | siRNA |
Disease name | diabetic retinopathy (DR) |
Species | Rattus norvegicus |
Tissues/Cell_line | Müller cells |
Methods | immunostaining, TUNEL assay, Western blot, Co-immunoprecipitation, Electrophysiology, siRNA transfection |
Expression pattern | associated |
Functional description | SiRNA analysis in Müller cells cultures grown under high glucose experimental conditions corroborated that, when the expression of KChIP3 is 50% reduced, the number of cells expressing A type currents decreases significantly. |
PubMed ID | 22277672 |
Year | 2012 |
Title | Hyperglycemia induces early upregulation of the calcium sensor KChIP3/DREAM/calsenilin in the rat retina. |
Drug-related ncRNA | NO |
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